Effect of Load Volume on PSD and Temperature in High Shear Granulations

High-shear mixers are commonly used in the production of wet granulations. These granulations can be used for both immediate and controlled release dosage forms. Occasionally it is necessary to modify the batch size to meet production requirements. This study was done to determine the effect of product load volume in a high-shear granulation process using both immediate and controlled release formulations.

Download the PDF