Granurex Technology Integral to Novel Processing Technique
Freund-Vector’s GXR technology and Dow’s Ethocel™ HP allows customers to coat multiparticulates without the need for solvent or aqueous-based polymers. This new technology allows for improved productivity and shorter coating times while moving away from solvent-based polymers.
The dry powder laying process works by wetting the substrate with a plasticizer/water combination. The dry polymer is applied to the wet surface of the substrate and a liquid bridge occurs between the dry powder particles and the surface of the substrate. The wetting agent and dry powder are continually sprayed as the polymer layers are formed like a snowball rolling in snow. After sufficient drying, the dry power coated substrates are cured. Below is an illustration portraying the dry powder coating process.
![](https://www.freundglobal.com/wp-content/uploads/2017/09/dry-powder-layer-process.jpg)
The ‘rolling snowball effect’ is illustrated in the picture above. Watch the process by clicking on this link: Granurex Powder Coating Processing Video .
![](https://www.freundglobal.com/wp-content/uploads/2017/09/VFC-Lab-3-with-GXR-35-rotor-insert.jpg)
The advantages of processing Ethocel™ HP on a GXR insert are as follows:
- Solvent free
- Reduces manufacturing costs
- Increases productivity
- Reduces equipment needs (combines API layering and polymer layering)
To read or download this poster, Please click here.
We look forward to discussing how Freund-Vector’s GXR Technology can assist you with developing and manufacturing pharmaceutical products.