Processing of Extended Release Tablets Containing Carbopol® 971P NF Polymer by Top-Drive High Shear
To evaluate the aqueous granulation process in a pilot-scale top-drive high shear granulator for guaifenesin formulations containing (10% or 20% w/w) Carbopol® 971P NF polymer and to determine the effect of processing conditions on the granule and tablet properties and on drug release.